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CAS Number 213697-53-1
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Empirical Formula (Hill Notation) C26H36NP
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Molecular Weight 393.54
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MDL number MFCD02183572
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PubChem Substance ID 24882905
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Popular Documents: Datasheet (PDF)
Properties:
| Related Categories | Buchwald Ligands, Buchwald Ligands and Complexes, Catalysis and Inorganic Chemistry, Chemical Synthesis, Cross-Coupling, |
| InChI Key |
ZEMZPXWZVTUONV-UHFFFAOYSA |
| assay | 97% |
| mp | 121-124 °C(lit.) |
| ligand for | Arylations |
| Buchwald-Hartwig Cross Coupling Reaction | |
| Hydroaminations | |
| Kumada Coupling |
Description:
Application
Useful ligand for Pd-catalyzed C-N bond formation; amination of aryl halides containing hydroxyl, amide, or enolizable ketones.
DavePhos may be used as a ligand in the following reactions:
• Palladium catalyzed sp3 arylation of 2-substituted-N-iminopyridinium ylides with different aryl chlorides to yield functionalized pyridines.
• Preparation of functionalized benzylic sulfones via palladium-catalyzed Negishi cross-coupling between alkyl sulfones and aryl halides.
• C-C Coupling of 3-haloquinolines with aryl sulfinates via palladium-catalyzed desulfitative arylation to form the corresponding biaryl compounds.
Ligand used in a Pd-catalyzed Suzuki aryl-aryl coupling leading to benzodioxepines.
Packaging
1, 5, 25, 100 g in glass bottle
Legal Information
Usage subject to US Patents 6307087 and 6395916.
Safety:
GHS07
