• CAS Number 247940-06-3

• Empirical Formula (Hill Notation) C₂₄H₃₁P

• Molecular Weight 350.48

•  Beilstein Registry Number 8440533

•  MDL number MFCD01862441

•  PubChem Substance ID 24882909

• Popular Documents:  Datasheet (PDF)  |  Specification Sheet (PDF)  

Properties:

Description:

Application

Ligand for amination of aryl halides and triflates.

CyJohnPhos may be used in combination with a nickel catalyst for the Suzuki-Miyaura arylation of tertiary benzylic acetates with aryl boroxines to produce diaryl and triaryl quaternary stereocenters.

Ligand employed in the palladium-catalysed synthesis of 1,3,5-tris(2′-aminophenyl)benzene, a core building block for potential ionic receptors.

Packaging

1, 5, 25 g in glass bottle

Legal Information

Usage subject to US Patents 6307087 and 6395916.

General description

CyJohnPhos [(2-Biphenyl)dicyclohexylphosphine] is an air-stable, bulky and electron-rich monodentate biarylphosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions.

Safety: