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Sigma-Aldrich/Sibutramine hydrochloride solution/S-011-1ML/1ML
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CAS Number 125494-59-9
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Empirical Formula (Hill Notation) C17H26ClN · HCl · H2O
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Molecular Weight 334.32
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EC Number 200-659-6
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MDL number MFCD04039806
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PubChem Substance ID 329824413
Properties:
| Related Categories | Additional Standards, Analytical Standards, Analytical/Chromatography, Certified Reference Materials (CRMs), Certified Reference Materials from Cerilliant, |
| grade | certified reference material |
| InChI Key |
KFNNPQDSPLWLCX-UHFFFAOYSA |
| feature | Snap-N-Spike®/Snap-N-Shoot® |
| packaging | ampule of 1 mL |
| concentration | 1.0 mg/mL in methanol (as free base) |
| format | single component solution |
| storage temp. | −20°C |
Description:
Biochem/physiol Actions
Sibutramine is a serotonin and noradrenaline reuptake inhibitor (SNRI). It is an antiobesity drug, which decreases calorie intake and increases energy expanditure. Sibutramine antagonizes MPTP-induced dopamine depletion in mouse brain.
General description
Sibutramine, a SNRI and anorectant, was marketed as a treatment for obesity until 2010 when it was removed from the market over concerns of potential adverse cardiovascular side effects. Sold under trade names Reductil, Meridia®, and Subitrex, this sibutramine Snap-N-Spike® reference solution is applicable for use in LC/MS or GC/MS applications for clinical toxicology and forensic analysis.
Legal Information
Meridia is a registered trademark of Abbott Laboratories Corp.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Cerilliant Corporation
Safety:


GHS02, GHS06, GHS08

