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Sigma-Aldrich/Fondaparinux sodium identification/1282718-30MG/30MG
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CAS Number 114870-03-0
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Empirical Formula (Hill Notation) C31H43N3O49S8 · 10Na
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Molecular Weight 1728.08
Properties:
| Related Categories | Analytical Standards, Analytical/Chromatography, Pharmacopeia & Metrological Institutes Standards, USP Standards, USP Standards E - F |
Description:
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia
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Other Notes
Sales restrictions may apply.
USP issued SDS can be found here.
Biochem/physiol Actions
Fondaparinux sodium is an antithrombotic anticoagulant, a Factor Xa inhibitor. Fondaparinux sodium is chemically related to low molecular weight heparins. Its pentasaccharide structure corresponds to the antithrombin III (ATIII) binding site of heparin. Fondaparinux sodium binding at this site potentiates the natural inhibitory effect of ATIII against factor Xa by a factor of approximately 300, which results in inhibition of thrombin generation.
