Properties:
| RelatedCategories | Analytical/Chromatography,HPLC,HPLC&FPLCColumnsforBiopolymerSeparations,TSKgelGelFiltrationColumnsforProteinsandotherBiopolymers,TSKgelGelFiltrationColumnstoAnalyzemAbPurityandAggregates, |
| mfr.no. | TosohSuperSWHRGuard,22857 |
| parameter | ≤0.5Msaltconcentration |
| 0-100%aqueoussolubleorganicsolvents | |
| 1mL/minflowrate | |
| 10-30°Ctemperature | |
| L×I.D. | 4 cm×6 mm |
| matrix | silicaparticleplatform |
Description:
Generaldescription
TheTSKgelSuperSWandUltraSWmAbcolumnsconsistofthreespecializedcolumnsdesignedfortheseparationandanalysisofmonoclonalantibodies(mAb).WhilemAbscanbeanalyzedusingmanydifferentmodesofHPLC,sizeexclusionisbesttodeterminethelevelofaggregation,dimerformation,andfragmentation,makingitthebestmethodforheterogeneitystudies.TSKgelSuperSWmAbHRcolumnsareoptimizedforhighresolutionanalysisofmAbmonomeranddimer;these30cmx7.8mmIDslica-basedstainlesssteelcolumnsofferreducedlot-to-lotvariation,longcolumnlife,reductionofunspecifiedadsorption,andsuperiorrecoveryofaggregates.TheTSKgelSuperSWmAbcolumnsutilizeauniquepore-controlledtechnology,whichproducesashallowcalibrationcurveinthemolecularweightregionofatypicalmonoclonalantibody.ThecalibrationcurvefortheTSKgelSuperSWmAbHRcolumnissimilartothatoftheindustry-leADIngTSKgelG3000SWxlcolumnandhasashallowerslopethantheTSKgelUltraSWAggregatecolumnaroundthemolecularweightrangeofgamma-globulin.Thisshallowcalibrationcurveproduceshighresolutionseparations.
Physicalform
Shippedin0.05%NaN3and0.1MNa2SO4in0.1Mphosphatebuffer,pH6.7.
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DiscoverLiChropurreagentsidealforHPLCorLC-MSanalysis
LegalInformation
TSKgelisaregisteredtrademarkofTosohCorporation
