Properties:

Description:

Application

Sample Preparation, HPLC

General description

Supel^™ Genie HybridSPE^® online cartridges have been developed as an alternative to traditional 96-well plate and individual cartridge formats for phospholipid removal and sample preparation. The HybridSPE online cartridges have been designed for online phospholipid removal allowing direct injection of protein precipitated samples for LC/MS analysis. When the samples flow through the HybridSPE online traps, the phospholipids are retained while the analytes of interest flow through.

For first time use, this starter kit is required to obtain reusable universal hardware that will fit all Supel Genie Online SPE cartridges.

LC instrumentation must be configured to accommodate Online SPE cartridges. Please see instrument setup diagram in data sheet 55327-U

Please contact techserv@sial.com <mailto:techserv@sial.com> for more information on setup and hardware.

Features and Benefits

• Provides cleaner samples for longer column life, less instrument downtime, and more accurate and reproducible data
• Automation saves time, decreases costs, and eliminates human error
• Unique Lewis acid/base retention mechanism effectively remove >95% of phospholipids from both hydrophilic and hydrophobic analytes of interest (unlike competitive chemistries) eliminating phospholipid-induced ion suppression
• Highly reproducible, consistent product performance
• Starter kit comes with reusable universal hardware (fits any of the Supel Genie Online SPE cartridges) and 1 cartridge
• Additional cartridges are also available in packs of 2 or 6

Legal Information

HybridSPE is a registered trademark of Sigma-Aldrich Co. LLC

Supel is a trademark of Sigma-Aldrich Co. LLC