CASNumber58-08-2
EmpiricalFormula(HillNotation)C8H10N4O2
MolecularWeight194.19
BeilsteinRegistryNumber17705
ECNumber200-362-1
MDLnumberMFCD00005758
PubChemSubstanceID329774763
Properties:
RelatedCategories | AnalyticalStandards,Analytical/Chromatography,EPStandards,EPStandardsC-D,Pharmacopeia&MetrologicalInstitutesStandards |
Description:
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Generaldescription
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Packaging
Unitquantity:70mg.Subjecttochange.TheproductisdeliveredassuppliedbytheissuingPharmacopoeia.Forthecurrentunitquantity,pleasevisittheEDQMreferencesubtancecatalogue.
Biochem/physiolActions
Acentralnervoussystemstimulantbelievedtoactthroughadenosinereceptorsandmonoamineneurotransmitters.ItisanadenosinereceptorantagoNISTandadenosine3′,5′-cyclicmonophosphate(cAMP)phosphodiesteraseinhibitor.Thus,levelsofcAMPincreaseincellsfollowingtreatmentwithcaffeine.Ithasbeenreportedtoaffectcellularcalciumlevels,releasingcalciumfromintracellularstores.Itoverridesthecellcycleeffectsofvariouschemicalssuchasproteaseinhibitors,preventingapoptosis;andithasbeenshowntoinhibitcellularDNArepairmechanisms.